Emflaza

Deflazacort

Emflaza is a corticosteroid indicated for the treatment of Duchenne muscular dystrophy (DMD) in patients at the age of 5 and older.

Package	Per pill	Price	Savings
180 tablet	£ 35.94	£ 6469.66£ 35.94	£ 11438.29
120 tablet	£ 41.47	£ 4976.09£ 41.47	£ 6962.54
90 tablet	£ 49.76	£ 4478.23£ 49.76	£ 4475.74
60 tablet	£ 62.19	£ 3731.45£ 62.19	£ 2237.87
30 tablet	£ 99.49	£ 2984.66£ 99.49

Package	Per pill	Price	Savings
120 tablet Free AirMail shipping Hot	£ 228.16	£ 27379.70£ 228.16	£ 4968.62
90 tablet Free AirMail shipping Hot	£ 240.60	£ 21654.33£ 240.60	£ 2606.91
60 tablet Free AirMail shipping Hot	£ 248.89	£ 14933.25£ 248.89	£ 1240.91
36 tablet Free AirMail shipping Hot	£ 262.69	£ 9456.81£ 262.69	£ 247.68
24 tablet	£ 269.57	£ 6469.66£ 269.57

Package	Per pill	Price	Savings
90 tablet Free AirMail shipping Hot	£ 276.56	£ 24890.41£ 276.56	£ 4971.73
60 tablet Free AirMail shipping Hot	£ 298.67	£ 17920.40£ 298.67	£ 1987.70
36 tablet Free AirMail shipping Hot	£ 318.01	£ 11448.24£ 318.01	£ 496.61
24 tablet Free AirMail shipping Hot	£ 331.80	£ 7963.24£ 331.80

Brand(s)

Manufacturer

Lupin

Disease(s)

Duchenne Muscular Dystrophy / DMD

Deflazacort tablets

What is this medicine?

Deflazacort a corticosteroid indicated for the treatment of Duchenne muscular dystrophy (DMD) in patients 5 years of age and older.

What should I tell my health care providers before I take this medicine?

They need to know if you have any of these conditions:

Hypersensitivity to deflazacort;
Alterations in Endocrine Function: Hypothalamic-pituitary-adrenal axis suppression, Cushing’s syndrome, and hyperglycemia;
Immunosuppression and Increased Risk of Infection: Increased risk of new, exacerbation, dissemination, or reactivation of latent infections, which can be severe and at times fatal;
Alterations in Cardiovascular/Renal Function: elevated blood pressure and sodium, and for decreased potassium level;
Gastrointestinal Perforation: GI disorders;
Behavioral and Mood Disturbances: euphoria, insomnia, mood swings, personality changes, severe depression, and psychosis;
Effects on Bones: decreases in bone mineral density;
Serious Skin Rashes;
Ophthalmic Effects: May include cataracts, infections, and glaucoma;
Vaccination: Do not administer live or live attenuated vaccines to patients receiving immunosuppressive doses of corticosteroids.

How should I use this medicine?

The recommended once-daily dosage is approximately 0.9 mg/kg/day administered orally. Discontinue gradually when administered for more than a few day..

What may interact with this medicine?

Moderate or strong CYP3A4 inhibitors: Give one third of the recommended dosage;
Avoid use of moderate or strong CYP3A4 inducers, as they may reduce efficacy.

What side effects may I notice from this medicine?

The most common adverse reactions are Cushingoid appearance, weight increased, increased appetite, upper respiratory tract infection, cough, pollakiuria, hirsutism, central obesity, and nasopharyngitis.

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