Emflaza

Deflazacort

Emflaza is a corticosteroid indicated for the treatment of Duchenne muscular dystrophy (DMD) in patients at the age of 5 and older.
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Package Per pill Price Savings Order
180 tablet
C$ 0.99
C$ 177.39C$ 0.99
C$ 313.63
120 tablet
C$ 1.14
C$ 136.44C$ 1.14
C$ 190.91
90 tablet
C$ 1.36
C$ 122.79C$ 1.36
C$ 122.72
60 tablet
C$ 1.71
C$ 102.31C$ 1.71
C$ 61.36
30 tablet
C$ 2.73
C$ 81.84C$ 2.73
Package Per pill Price Savings Order
120 tablet
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C$ 6.26
C$ 750.74C$ 6.26
C$ 136.24
90 tablet
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C$ 6.60
C$ 593.75C$ 6.60
C$ 71.48
60 tablet
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C$ 6.82
C$ 409.46C$ 6.82
C$ 34.03
36 tablet
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C$ 7.20
C$ 259.30C$ 7.20
C$ 6.79
24 tablet
C$ 7.39
C$ 177.39C$ 7.39
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90 tablet
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C$ 7.58
C$ 682.48C$ 7.58
C$ 136.32
60 tablet
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C$ 8.19
C$ 491.37C$ 8.19
C$ 54.50
36 tablet
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C$ 8.72
C$ 313.90C$ 8.72
C$ 13.62
24 tablet
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C$ 9.10
C$ 218.35C$ 9.10
Emflaza

Brand(s)

Manufacturer

  • Lupin

Disease(s)

  • Duchenne Muscular Dystrophy / DMD

Deflazacort tablets

What is this medicine?

Deflazacort a corticosteroid indicated for the treatment of Duchenne muscular dystrophy (DMD) in patients 5 years of age and older.

What should I tell my health care providers before I take this medicine?

They need to know if you have any of these conditions:

  • Hypersensitivity to deflazacort;
  • Alterations in Endocrine Function: Hypothalamic-pituitary-adrenal axis suppression, Cushing’s syndrome, and hyperglycemia;
  • Immunosuppression and Increased Risk of Infection: Increased risk of new, exacerbation, dissemination, or reactivation of latent infections, which can be severe and at times fatal;
  • Alterations in Cardiovascular/Renal Function: elevated blood pressure and sodium, and for decreased potassium level;
  • Gastrointestinal Perforation: GI disorders;
  • Behavioral and Mood Disturbances: euphoria, insomnia, mood swings, personality changes, severe depression, and psychosis;
  • Effects on Bones: decreases in bone mineral density;
  • Serious Skin Rashes;
  • Ophthalmic Effects: May include cataracts, infections, and glaucoma;
  • Vaccination: Do not administer live or live attenuated vaccines to patients receiving immunosuppressive doses of corticosteroids.

How should I use this medicine?

The recommended once-daily dosage is approximately 0.9 mg/kg/day administered orally. Discontinue gradually when administered for more than a few day..

What may interact with this medicine?

  • Moderate or strong CYP3A4 inhibitors: Give one third of the recommended dosage;
  • Avoid use of moderate or strong CYP3A4 inducers, as they may reduce efficacy.

What side effects may I notice from this medicine?

The most common adverse reactions are Cushingoid appearance, weight increased, increased appetite, upper respiratory tract infection, cough, pollakiuria, hirsutism, central obesity, and nasopharyngitis.