Emflaza

Deflazacort

Emflaza is a corticosteroid indicated for the treatment of Duchenne muscular dystrophy (DMD) in patients at the age of 5 and older.
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Package Per pill Price Savings Order
180 tablet
C$ 1.00
C$ 179.92C$ 1.00
C$ 318.09
120 tablet
C$ 1.15
C$ 138.38C$ 1.15
C$ 193.62
90 tablet
C$ 1.38
C$ 124.54C$ 1.38
C$ 124.47
60 tablet
C$ 1.73
C$ 103.77C$ 1.73
C$ 62.23
30 tablet
C$ 2.77
C$ 83.00C$ 2.77
Package Per pill Price Savings Order
120 tablet
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C$ 6.35
C$ 761.41C$ 6.35
C$ 138.17
90 tablet
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C$ 6.69
C$ 602.19C$ 6.69
C$ 72.50
60 tablet
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C$ 6.92
C$ 415.28C$ 6.92
C$ 34.51
36 tablet
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C$ 7.31
C$ 262.99C$ 7.31
C$ 6.89
24 tablet
C$ 7.50
C$ 179.92C$ 7.50
Package Per pill Price Savings Order
90 tablet
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C$ 7.69
C$ 692.18C$ 7.69
C$ 138.26
60 tablet
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C$ 8.31
C$ 498.35C$ 8.31
C$ 55.28
36 tablet
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C$ 8.84
C$ 318.37C$ 8.84
C$ 13.81
24 tablet
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C$ 9.23
C$ 221.45C$ 9.23
Emflaza

Brand(s)

Manufacturer

  • Lupin

Disease(s)

  • Duchenne Muscular Dystrophy / DMD

Deflazacort tablets

What is this medicine?

Deflazacort a corticosteroid indicated for the treatment of Duchenne muscular dystrophy (DMD) in patients 5 years of age and older.

What should I tell my health care providers before I take this medicine?

They need to know if you have any of these conditions:

  • Hypersensitivity to deflazacort;
  • Alterations in Endocrine Function: Hypothalamic-pituitary-adrenal axis suppression, Cushing’s syndrome, and hyperglycemia;
  • Immunosuppression and Increased Risk of Infection: Increased risk of new, exacerbation, dissemination, or reactivation of latent infections, which can be severe and at times fatal;
  • Alterations in Cardiovascular/Renal Function: elevated blood pressure and sodium, and for decreased potassium level;
  • Gastrointestinal Perforation: GI disorders;
  • Behavioral and Mood Disturbances: euphoria, insomnia, mood swings, personality changes, severe depression, and psychosis;
  • Effects on Bones: decreases in bone mineral density;
  • Serious Skin Rashes;
  • Ophthalmic Effects: May include cataracts, infections, and glaucoma;
  • Vaccination: Do not administer live or live attenuated vaccines to patients receiving immunosuppressive doses of corticosteroids.

How should I use this medicine?

The recommended once-daily dosage is approximately 0.9 mg/kg/day administered orally. Discontinue gradually when administered for more than a few day..

What may interact with this medicine?

  • Moderate or strong CYP3A4 inhibitors: Give one third of the recommended dosage;
  • Avoid use of moderate or strong CYP3A4 inducers, as they may reduce efficacy.

What side effects may I notice from this medicine?

The most common adverse reactions are Cushingoid appearance, weight increased, increased appetite, upper respiratory tract infection, cough, pollakiuria, hirsutism, central obesity, and nasopharyngitis.